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Early MRI Findings in Patients Receiving Tissue Plasminogen Activator Predict Outcome: Insights into the Pathophysiology of Acute Stroke in the Thrombolysis Era Ann Neurol 55:105-112, Chalela,J.A.,et al, 2004 See this aricle in Pubmed Article Abstract We propose MTT lesion volume decrease more than 30% 2 hours after tPA as an early marker of long-term clinical benefit of thrombolytic therapy.

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